Reversible monomer-oligomer transition in human prion protein
نویسندگان
چکیده
منابع مشابه
Unique Properties of the Rabbit Prion Protein Oligomer
Prion diseases, also known as transmissible spongiform encephalopathies (TSEs), are a group of fatal neurodegenerative disorders infecting both humans and animals. Recent works have demonstrated that the soluble prion protein oligomer (PrPO), the intermediate of the conformational transformation from the host-derived cellular form (PrPC) to the disease-associated Scrapie form (PrPSc), exerts th...
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ژورنال
عنوان ژورنال: Prion
سال: 2008
ISSN: 1933-6896,1933-690X
DOI: 10.4161/pri.2.3.7148